Hello,
Are you using a location on a network share? If yes, please update to the latest version and check if the problem persists. You can download it here:
https://www.boxcryptor.com/l/download-windows
If the problem should still exist or you're not using a network share, you can help us by creating a debug log using (also using the latest 2.2 version):
https://support.boxcryptor.com/display/BCWINEN/How+to+create+a+Debug+log
Best regards,
Robert